Negative

For negatives, we use there isn't or there's not (= there is not) for singular and there aren't (= there are not) for plural. 

There isn't a pharmacy near the hotel.
There aren't any restaurants near the hotel.

We often use there isn't a + singular noun, there isn't any + uncountable noun and there aren't any + plural noun.

There isn't a café near here.
There isn't any milk.
There aren't any toilets in the park.

To show that the negative is important, we also often use there is no + uncountable noun and there are no + plural noun. (It is possible to use there is no + singular noun, but it's not as common.)

There's no milk.
There are no toilets in the park.